Tailoring hydrogel adhesion to polydimethylsiloxane substrates using polysaccharide glue

Chaenyung Cha; Eleni Antoniadou; Minkyung Lee; Jae Hyun Jeong; Wylie W. Ahmed; Taher A. Saif; Stephen A. Boppart; Hyunjoon Kong

doi:10.1002/anie.201302925

Tailoring hydrogel adhesion to polydimethylsiloxane substrates using polysaccharide glue

Chaenyung Cha, Eleni Antoniadou, Minkyung Lee, Jae Hyun Jeong, Wylie W. Ahmed, Taher A. Saif, Stephen A. Boppart, Hyunjoon Kong

Research output: Contribution to journal › Article › peer-review

Abstract

Hydrogel meets silicone: The chemical functionalization of a polydimethylsiloxane (PDMS) surface with polysaccharide "glue" induces a strong, permanent adhesion between the hydrogel and PDMS. This hydrogel-coated silicone substrate was useful for controlling cellular organization under mechanical stretching (see picture) and also in fabricating microfluidic devices filled with the gel.

Original language	English (US)
Pages (from-to)	6949-6952
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	27
DOIs	https://doi.org/10.1002/anie.201302925
State	Published - Jul 1 2013

Keywords

alginate
hydrogels
mechanical stimulation
microfluidics
polydimethylsiloxanes

ASJC Scopus subject areas

General Chemistry
Catalysis

Online availability

10.1002/anie.201302925

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AU - Antoniadou, Eleni

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AU - Jeong, Jae Hyun

AU - Ahmed, Wylie W.

AU - Saif, Taher A.

AU - Boppart, Stephen A.

AU - Kong, Hyunjoon

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AB - Hydrogel meets silicone: The chemical functionalization of a polydimethylsiloxane (PDMS) surface with polysaccharide "glue" induces a strong, permanent adhesion between the hydrogel and PDMS. This hydrogel-coated silicone substrate was useful for controlling cellular organization under mechanical stretching (see picture) and also in fabricating microfluidic devices filled with the gel.

KW - alginate

KW - hydrogels

KW - mechanical stimulation

KW - microfluidics

KW - polydimethylsiloxanes

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Tailoring hydrogel adhesion to polydimethylsiloxane substrates using polysaccharide glue

Abstract

Keywords

ASJC Scopus subject areas

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