Hydrogel meets silicone: The chemical functionalization of a polydimethylsiloxane (PDMS) surface with polysaccharide "glue" induces a strong, permanent adhesion between the hydrogel and PDMS. This hydrogel-coated silicone substrate was useful for controlling cellular organization under mechanical stretching (see picture) and also in fabricating microfluidic devices filled with the gel.

Original languageEnglish (US)
Pages (from-to)6949-6952
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number27
StatePublished - Jul 1 2013


  • alginate
  • hydrogels
  • mechanical stimulation
  • microfluidics
  • polydimethylsiloxanes

ASJC Scopus subject areas

  • General Chemistry
  • Catalysis


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