System modeling and evaluation of a prototype inverted-compound eye gamma camera for the second generation MR compatible SPECT

Xiaochun Lai, Elena M. Zannoni, Jonathan George, Ling Jian Meng

Research output: Contribution to journalReview article

Abstract

We have reported the design of the MRC-SPECT-II system based on the inverted-compound-eye (ICE) gamma camera to offer a >1% detection efficiency while maintaining a sub-500μm imaging resolution (Lai and Meng, 2018). One of the key challenges of using the ICE camera for SPECT imaging is whether one could develop an accurate point response function (PRF), given its complex aperture design and low fractionation accuracy of 3D printing. In this work, we will discuss (I) a combined experimental and analytical approach for deriving the precise PRF, and (II) an experimental imaging study to demonstrate the feasibility of using the ICE-camera for acquiring high-quality SPECT images with a sub-500μm resolution. These studies would help to overcome one of the major hurdles for implement ICE-cameras for practical SPECT imaging.

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Cameras
cameras
prototypes
Imaging techniques
evaluation
Fractionation
fractionation
printing
Image quality
Printing
apertures

Keywords

  • CdTe
  • Compound eye
  • SPECT modeling
  • SPECT/MRI

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

@article{3aa2b40f98d047a481a99cb9667b3389,
title = "System modeling and evaluation of a prototype inverted-compound eye gamma camera for the second generation MR compatible SPECT",
abstract = "We have reported the design of the MRC-SPECT-II system based on the inverted-compound-eye (ICE) gamma camera to offer a >1{\%} detection efficiency while maintaining a sub-500μm imaging resolution (Lai and Meng, 2018). One of the key challenges of using the ICE camera for SPECT imaging is whether one could develop an accurate point response function (PRF), given its complex aperture design and low fractionation accuracy of 3D printing. In this work, we will discuss (I) a combined experimental and analytical approach for deriving the precise PRF, and (II) an experimental imaging study to demonstrate the feasibility of using the ICE-camera for acquiring high-quality SPECT images with a sub-500μm resolution. These studies would help to overcome one of the major hurdles for implement ICE-cameras for practical SPECT imaging.",
keywords = "CdTe, Compound eye, SPECT modeling, SPECT/MRI",
author = "Xiaochun Lai and Zannoni, {Elena M.} and Jonathan George and Meng, {Ling Jian}",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.nima.2019.04.001",
language = "English (US)",
journal = "Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",
issn = "0168-9002",
publisher = "Elsevier",

}

TY - JOUR

T1 - System modeling and evaluation of a prototype inverted-compound eye gamma camera for the second generation MR compatible SPECT

AU - Lai, Xiaochun

AU - Zannoni, Elena M.

AU - George, Jonathan

AU - Meng, Ling Jian

PY - 2019/1/1

Y1 - 2019/1/1

N2 - We have reported the design of the MRC-SPECT-II system based on the inverted-compound-eye (ICE) gamma camera to offer a >1% detection efficiency while maintaining a sub-500μm imaging resolution (Lai and Meng, 2018). One of the key challenges of using the ICE camera for SPECT imaging is whether one could develop an accurate point response function (PRF), given its complex aperture design and low fractionation accuracy of 3D printing. In this work, we will discuss (I) a combined experimental and analytical approach for deriving the precise PRF, and (II) an experimental imaging study to demonstrate the feasibility of using the ICE-camera for acquiring high-quality SPECT images with a sub-500μm resolution. These studies would help to overcome one of the major hurdles for implement ICE-cameras for practical SPECT imaging.

AB - We have reported the design of the MRC-SPECT-II system based on the inverted-compound-eye (ICE) gamma camera to offer a >1% detection efficiency while maintaining a sub-500μm imaging resolution (Lai and Meng, 2018). One of the key challenges of using the ICE camera for SPECT imaging is whether one could develop an accurate point response function (PRF), given its complex aperture design and low fractionation accuracy of 3D printing. In this work, we will discuss (I) a combined experimental and analytical approach for deriving the precise PRF, and (II) an experimental imaging study to demonstrate the feasibility of using the ICE-camera for acquiring high-quality SPECT images with a sub-500μm resolution. These studies would help to overcome one of the major hurdles for implement ICE-cameras for practical SPECT imaging.

KW - CdTe

KW - Compound eye

KW - SPECT modeling

KW - SPECT/MRI

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U2 - 10.1016/j.nima.2019.04.001

DO - 10.1016/j.nima.2019.04.001

M3 - Review article

AN - SCOPUS:85064659140

JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

SN - 0168-9002

ER -