Synthetic gene networks: the next wave in biotechnology?

Research output: Contribution to journalReview article

Abstract

Engineering novel, reusable gene networks to provide greater control over cellular processes is one of the goals of the emerging discipline of synthetic biology. This article reviews the landmark literature pertaining to the development of synthetic gene networks, the engineering framework used to design and characterize them and the technological developments on the horizon that could potentially advance the field in new directions. As gene network engineering enters its second decade, an attempt is also made to outline the challenges in advancing this nascent field, especially with regard to the practical limitations of component reusability and reliability and the opportunities that present themselves in the development of novel gene expression controllers and single-cell biosensors.

Original languageEnglish (US)
Pages (from-to)368-374
Number of pages7
JournalTrends in Biotechnology
Volume27
Issue number6
DOIs
StatePublished - Jun 1 2009

Fingerprint

Synthetic Genes
Gene Regulatory Networks
Biotechnology
Genes
Synthetic Biology
Reusability
Biosensing Techniques
Gene expression
Biosensors
Gene Expression
Controllers

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Synthetic gene networks : the next wave in biotechnology? / Bhalerao, Kaustubh D.

In: Trends in Biotechnology, Vol. 27, No. 6, 01.06.2009, p. 368-374.

Research output: Contribution to journalReview article

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