Synthetic biology for therapeutic applications

Zhanar Abil, Xiong Xiong, Huimin Zhao

Research output: Contribution to journalReview articlepeer-review


Synthetic biology is a relatively new field with the key aim of designing and constructing biological systems with novel functionalities. Today, synthetic biology devices are making their first steps in contributing new solutions to a number of biomedical challenges, such as emerging bacterial antibiotic resistance and cancer therapy. This review discusses some synthetic biology approaches and applications that were recently used in disease mechanism investigation and disease modeling, drug discovery and production, as well as vaccine development and treatment of infectious diseases, cancer, and metabolic disorders.

Original languageEnglish (US)
Pages (from-to)322-331
Number of pages10
JournalMolecular pharmaceutics
Issue number2
StatePublished - Feb 2 2015


  • cancer treatment
  • disease mechanism
  • drug discovery
  • infectious diseases
  • metabolic disorders
  • synthetic biology
  • therapeutic treatment
  • vaccine development

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery


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