Synthesis of unsymmetrical biaryls from arylsilacyclobutanes

Scott E Denmark, Zhicai Wu

Research output: Contribution to journalArticle

Abstract

(formula presented) Aryl(fluoro)silacyclobutanes and aryl(chloro)silacyclobutanes have been found to undergo cross-coupling reactions with aryl iodides. The rate of reaction and extent of homocoupling were dramatically affected by the addition of ligands for the palladium catalyst. With (t-Bu) 3 P a wide range of electronically and structurally diverse unsymmetrical biaryls have been prepared in good to excellent yields.

Original languageEnglish (US)
Pages (from-to)1495-1498
Number of pages4
JournalOrganic Letters
Volume1
Issue number9
DOIs
StatePublished - Nov 4 1999

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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