Synthesis of 14C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins

Grant A. Krafft, Marvin F. Reich, John A. Katzenellenbogen

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis of [14C]‐10,11‐Epoxy‐(2E,6E)‐farnesyl diazoacetate in one vessel, starting from [14C]‐glyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.

Original languageEnglish (US)
Pages (from-to)591-596
Number of pages6
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume19
Issue number4
DOIs
StatePublished - Apr 1982

Keywords

  • Diazoacetate
  • Juvenile Hormone Analog
  • Photoaffinity Labeling

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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