Synthesis of 14C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins

Grant A. Krafft; Marvin F. Reich; John A. Katzenellenbogen

doi:10.1002/jlcr.2580190413

Synthesis of ¹⁴C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins

Grant A. Krafft, Marvin F. Reich, John A. Katzenellenbogen

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of [¹⁴C]‐10,11‐Epoxy‐(2E,6E)‐farnesyl diazoacetate in one vessel, starting from [¹⁴C]‐glyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.

Original language	English (US)
Pages (from-to)	591-596
Number of pages	6
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	19
Issue number	4
DOIs	https://doi.org/10.1002/jlcr.2580190413
State	Published - Apr 1982

Keywords

Diazoacetate
Juvenile Hormone Analog
Photoaffinity Labeling

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Radiology Nuclear Medicine and imaging
Drug Discovery
Spectroscopy
Organic Chemistry

Online availability

10.1002/jlcr.2580190413

Library availability

Discover UIUC Full Text

Cite this

Synthesis of ¹⁴C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins. / Krafft, Grant A.; Reich, Marvin F.; Katzenellenbogen, John A.
In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 19, No. 4, 04.1982, p. 591-596.

Research output: Contribution to journal › Article › peer-review

@article{416b52e07d544daeb901dd06819dd60e,

title = "Synthesis of 14C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins",

abstract = "The synthesis of [14C]‐10,11‐Epoxy‐(2E,6E)‐farnesyl diazoacetate in one vessel, starting from [14C]‐glyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.",

keywords = "Diazoacetate, Juvenile Hormone Analog, Photoaffinity Labeling",

author = "Krafft, {Grant A.} and Reich, {Marvin F.} and Katzenellenbogen, {John A.}",

year = "1982",

month = apr,

doi = "10.1002/jlcr.2580190413",

language = "English (US)",

volume = "19",

pages = "591--596",

journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

issn = "0362-4803",

publisher = "John Wiley & Sons, Ltd.",

number = "4",

}

TY - JOUR

T1 - Synthesis of 14C‐labeled 10,11‐epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins

AU - Krafft, Grant A.

AU - Reich, Marvin F.

AU - Katzenellenbogen, John A.

PY - 1982/4

Y1 - 1982/4

N2 - The synthesis of [14C]‐10,11‐Epoxy‐(2E,6E)‐farnesyl diazoacetate in one vessel, starting from [14C]‐glyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.

AB - The synthesis of [14C]‐10,11‐Epoxy‐(2E,6E)‐farnesyl diazoacetate in one vessel, starting from [14C]‐glyoxylic acid, is described. This compound is useful as a potential photoaffinity labeling agent for juvenile hormone binding sites.

KW - Diazoacetate

KW - Juvenile Hormone Analog

KW - Photoaffinity Labeling

UR - http://www.scopus.com/inward/record.url?scp=0019951607&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019951607&partnerID=8YFLogxK

U2 - 10.1002/jlcr.2580190413

DO - 10.1002/jlcr.2580190413

M3 - Article

AN - SCOPUS:0019951607

SN - 0362-4803

VL - 19

SP - 591

EP - 596

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 4

ER -