TY - JOUR
T1 - Synthesis of Cyclophanes Derived from l-Amino-3,7-dialkyl-4-methylnaphthalenes
AU - Kemp, D. S.
AU - Garst, M. E.
AU - Harper, R. W.
AU - Cox, D. D.
AU - Carlson, D.
AU - Denmark, S.
PY - 1979
Y1 - 1979
N2 - A practical five-step route is described to 1,6-bis(l,-amino-3'-carbethoxy-4'-methyl-7'-naphthyl)hexane (6) in 23% yield from 1,6-diphenylhexane. From 6 are prepared two 3,7-bridged naphthalene-derived cyclophanes, 1,8-[3,7][l-(dimethylamino)-4-methylnaphtha]-3,6-dithiacyclotetradecaphane (15) and 1,11-[3,7][l-(dimethylamino)-4-methylnaphtha]-2,10-diketo-3,9-di-iV-methylazacycloheptadecaphane1 (13).
AB - A practical five-step route is described to 1,6-bis(l,-amino-3'-carbethoxy-4'-methyl-7'-naphthyl)hexane (6) in 23% yield from 1,6-diphenylhexane. From 6 are prepared two 3,7-bridged naphthalene-derived cyclophanes, 1,8-[3,7][l-(dimethylamino)-4-methylnaphtha]-3,6-dithiacyclotetradecaphane (15) and 1,11-[3,7][l-(dimethylamino)-4-methylnaphtha]-2,10-diketo-3,9-di-iV-methylazacycloheptadecaphane1 (13).
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U2 - 10.1021/jo00393a001
DO - 10.1021/jo00393a001
M3 - Article
AN - SCOPUS:33845561760
SN - 0022-3263
VL - 44
SP - 4469
EP - 4473
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 25
ER -