Synthesis of an ethylene glycol cross-linked amino acid

Mengfei Ho, Weiheng Wang, Maria Douvlos, Thuha Pham, Klock Timothy

Research output: Contribution to journalArticlepeer-review


Synthesis of an ethylene glycol-containing amino acid, (2R,9S)-N2-Cbz-N9-Boc,2,9-diamino-4,7-dioxadecanedioic acid 1-phenacyl 10-methyl diester 1, was studied through direct alkylation of N-Boc-L-serine and through BF3-catalyzed ring opening of N-acylaziridinecarboxylates.

Original languageEnglish (US)
Pages (from-to)1283-1286
Number of pages4
JournalTetrahedron Letters
Issue number10
StatePublished - Mar 4 1991
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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