Syntheses and configurational assignments of the diastereomers of the 4-nitrophenyl esters of thymidine 3′-(N-phenyl phosphoramidate) and thymidine 5′-(N-phenyl phosphoramidate)

John A. Gerlt, Shujaath Mehdi, Jeffrey A. Coderre, William O. Rogers

Research output: Contribution to journalArticle

Abstract

The separated diastereomers of 3′-(4-nitrophenyl N-phenyl phosphoramidate)-5′-monomethoxytrityl thymidine and 3′-monomethoxytrityl-5′-(4-nitrophenyl N-phenyl phosphoramidate) thymidine have been prepared and their absolute configurations at phosphorus have been determined.

Original languageEnglish (US)
Pages (from-to)2385-2388
Number of pages4
JournalTetrahedron Letters
Volume21
Issue number25
DOIs
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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