Synchrotron FTIR imaging for the identification of cell types within human tissues

Michael J. Walsh, Michael J. Nasse, F. Nell Pounder, Virgilia Macias, Andre Kajdacsy-Balla, Carol Hirschmugl, Rohit Bhargava

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

Original languageEnglish (US)
Title of host publicationWIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources
Pages105-107
Number of pages3
DOIs
StatePublished - Feb 22 2010
Event5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, WIRMS 2009 - Banff, AB, Canada
Duration: Sep 13 2009Sep 17 2009

Publication series

NameAIP Conference Proceedings
Volume1214
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, WIRMS 2009
CountryCanada
CityBanff, AB
Period9/13/099/17/09

Fingerprint

synchrotrons
infrared spectroscopy
cells
diffraction
breast
acquisition
synchrotron radiation
infrared spectra
spatial resolution
spectroscopy

Keywords

  • Breast
  • Cancer
  • Cells
  • Focal plane array
  • Fourier Transform Infrared Spectroscopy
  • Infrared imaging
  • Prostate
  • Synchrotron

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Walsh, M. J., Nasse, M. J., Pounder, F. N., Macias, V., Kajdacsy-Balla, A., Hirschmugl, C., & Bhargava, R. (2010). Synchrotron FTIR imaging for the identification of cell types within human tissues. In WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources (pp. 105-107). (AIP Conference Proceedings; Vol. 1214). https://doi.org/10.1063/1.3326333

Synchrotron FTIR imaging for the identification of cell types within human tissues. / Walsh, Michael J.; Nasse, Michael J.; Pounder, F. Nell; Macias, Virgilia; Kajdacsy-Balla, Andre; Hirschmugl, Carol; Bhargava, Rohit.

WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources. 2010. p. 105-107 (AIP Conference Proceedings; Vol. 1214).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Walsh, MJ, Nasse, MJ, Pounder, FN, Macias, V, Kajdacsy-Balla, A, Hirschmugl, C & Bhargava, R 2010, Synchrotron FTIR imaging for the identification of cell types within human tissues. in WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources. AIP Conference Proceedings, vol. 1214, pp. 105-107, 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, WIRMS 2009, Banff, AB, Canada, 9/13/09. https://doi.org/10.1063/1.3326333
Walsh MJ, Nasse MJ, Pounder FN, Macias V, Kajdacsy-Balla A, Hirschmugl C et al. Synchrotron FTIR imaging for the identification of cell types within human tissues. In WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources. 2010. p. 105-107. (AIP Conference Proceedings). https://doi.org/10.1063/1.3326333
Walsh, Michael J. ; Nasse, Michael J. ; Pounder, F. Nell ; Macias, Virgilia ; Kajdacsy-Balla, Andre ; Hirschmugl, Carol ; Bhargava, Rohit. / Synchrotron FTIR imaging for the identification of cell types within human tissues. WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources. 2010. pp. 105-107 (AIP Conference Proceedings).
@inproceedings{a4af8f6e76564361bd5072f2947600fc,
title = "Synchrotron FTIR imaging for the identification of cell types within human tissues",
abstract = "The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.",
keywords = "Breast, Cancer, Cells, Focal plane array, Fourier Transform Infrared Spectroscopy, Infrared imaging, Prostate, Synchrotron",
author = "Walsh, {Michael J.} and Nasse, {Michael J.} and Pounder, {F. Nell} and Virgilia Macias and Andre Kajdacsy-Balla and Carol Hirschmugl and Rohit Bhargava",
year = "2010",
month = "2",
day = "22",
doi = "10.1063/1.3326333",
language = "English (US)",
isbn = "9780735407572",
series = "AIP Conference Proceedings",
pages = "105--107",
booktitle = "WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources",

}

TY - GEN

T1 - Synchrotron FTIR imaging for the identification of cell types within human tissues

AU - Walsh, Michael J.

AU - Nasse, Michael J.

AU - Pounder, F. Nell

AU - Macias, Virgilia

AU - Kajdacsy-Balla, Andre

AU - Hirschmugl, Carol

AU - Bhargava, Rohit

PY - 2010/2/22

Y1 - 2010/2/22

N2 - The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

AB - The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

KW - Breast

KW - Cancer

KW - Cells

KW - Focal plane array

KW - Fourier Transform Infrared Spectroscopy

KW - Infrared imaging

KW - Prostate

KW - Synchrotron

UR - http://www.scopus.com/inward/record.url?scp=76749135791&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76749135791&partnerID=8YFLogxK

U2 - 10.1063/1.3326333

DO - 10.1063/1.3326333

M3 - Conference contribution

AN - SCOPUS:76749135791

SN - 9780735407572

T3 - AIP Conference Proceedings

SP - 105

EP - 107

BT - WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources

ER -