Synchrotron FTIR imaging for the identification of cell types within human tissues

Michael J. Walsh, Michael J. Nasse, F. Nell Pounder, Virgilia Macias, Andre Kajdacsy-Balla, Carol Hirschmugl, Rohit Bhargava

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

Original languageEnglish (US)
Title of host publicationWIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources
Pages105-107
Number of pages3
DOIs
StatePublished - Feb 22 2010
Event5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, WIRMS 2009 - Banff, AB, Canada
Duration: Sep 13 2009Sep 17 2009

Publication series

NameAIP Conference Proceedings
Volume1214
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, WIRMS 2009
CountryCanada
CityBanff, AB
Period9/13/099/17/09

Keywords

  • Breast
  • Cancer
  • Cells
  • Focal plane array
  • Fourier Transform Infrared Spectroscopy
  • Infrared imaging
  • Prostate
  • Synchrotron

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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  • Cite this

    Walsh, M. J., Nasse, M. J., Pounder, F. N., Macias, V., Kajdacsy-Balla, A., Hirschmugl, C., & Bhargava, R. (2010). Synchrotron FTIR imaging for the identification of cell types within human tissues. In WIRMS 2009 - 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources (pp. 105-107). (AIP Conference Proceedings; Vol. 1214). https://doi.org/10.1063/1.3326333