Suspected toxicosis after topical administration of minoxidil in 2 cats

Camille DeClementi, Keith L. Bailey, Spencer C. Goldstein, Michael Scott Orser

Research output: Contribution to journalArticlepeer-review


Objective: To discuss the clinical presentation and necropsy findings of 2 cats after topical administration of a minoxidil solution. Additionally, a potential management plan is offered for future cases. Case summary: Two cats with dermal exposure to topical minoxidil solution were identified from the ASPCA Animal Poison Control Center (APCC) files. Both cats were presented with lethargy and dyspnea within 36 hours of exposure. The cats were hypothermic, and had pulmonary edema and pleural effusion present on thoracic radiography. Both cats died despite supportive care. Necropsy of both cats confirmed pleural effusion and pulmonary edema and indicated cardiac compromise. New or unique information provided: Topical administration of minoxidil solution may cause life-threatening pulmonary edema, pleural effusion, and cardiac dysfunction in the cat.

Original languageEnglish (US)
Pages (from-to)287-292
Number of pages6
JournalJournal of Veterinary Emergency and Critical Care
Issue number4
StatePublished - Dec 2004


  • Hypotensive agents
  • Pleural effusion
  • Pulmonary edema
  • Vasopressors

ASJC Scopus subject areas

  • veterinary(all)


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