Susceptibility, echo time shifts, and T2* considerations for functional magnetic resonance imaging

Bradley P. Sutton; Yue Zhuo

doi:10.1109/ISBI.2009.5193146

Susceptibility, echo time shifts, and T2* considerations for functional magnetic resonance imaging

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Magnetic susceptibility differences exist near the interface of air/tissue in the ventral brain in fMRI (functional magnetic resonance imaging). These susceptibility differences will not only cause field inhomogeneity and its gradients which will result in image artifacts, but also cause shifts in the echo time for gradients echo acquisitions. The echo time shifts are caused by shifts in the effective k-space trajectory due to the gradients of the field inhomogeneity. Previous work has shown and validated methods for estimating the echo time shift based on the effective k-space trajectory. In this work, we demonstrate that accurate estimation of the R2* decay map (R2*=1/T2*) not only need to account for the field map and its gradients, but also needs to include the echo time shift. These changes in T2* sensitivity are directly related to changes in sensitivity in BOLD (blood oxygenation level dependent) fMRI studies.

Original language	English (US)
Title of host publication	Proceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	From Nano to Macro, ISBI 2009
Pages	710-713
Number of pages	4
DOIs	https://doi.org/10.1109/ISBI.2009.5193146
State	Published - 2009
Event	2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States Duration: Jun 28 2009 → Jul 1 2009

Other

Other	2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Country	United States
City	Boston, MA
Period	6/28/09 → 7/1/09

Keywords

BOLD fMRI
Echo time shift
Field inhomogeneity
Magnetic susceptibility

ASJC Scopus subject areas

Biomedical Engineering
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/ISBI.2009.5193146

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Sutton, BP & Zhuo, Y 2009, Susceptibility, echo time shifts, and T2* considerations for functional magnetic resonance imaging. in Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009., 5193146, pp. 710-713, 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, Boston, MA, United States, 6/28/09. https://doi.org/10.1109/ISBI.2009.5193146

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abstract = "Magnetic susceptibility differences exist near the interface of air/tissue in the ventral brain in fMRI (functional magnetic resonance imaging). These susceptibility differences will not only cause field inhomogeneity and its gradients which will result in image artifacts, but also cause shifts in the echo time for gradients echo acquisitions. The echo time shifts are caused by shifts in the effective k-space trajectory due to the gradients of the field inhomogeneity. Previous work has shown and validated methods for estimating the echo time shift based on the effective k-space trajectory. In this work, we demonstrate that accurate estimation of the R2* decay map (R2*=1/T2*) not only need to account for the field map and its gradients, but also needs to include the echo time shift. These changes in T2* sensitivity are directly related to changes in sensitivity in BOLD (blood oxygenation level dependent) fMRI studies.",

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author = "Sutton, {Bradley P.} and Yue Zhuo",

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AB - Magnetic susceptibility differences exist near the interface of air/tissue in the ventral brain in fMRI (functional magnetic resonance imaging). These susceptibility differences will not only cause field inhomogeneity and its gradients which will result in image artifacts, but also cause shifts in the echo time for gradients echo acquisitions. The echo time shifts are caused by shifts in the effective k-space trajectory due to the gradients of the field inhomogeneity. Previous work has shown and validated methods for estimating the echo time shift based on the effective k-space trajectory. In this work, we demonstrate that accurate estimation of the R2* decay map (R2*=1/T2*) not only need to account for the field map and its gradients, but also needs to include the echo time shift. These changes in T2* sensitivity are directly related to changes in sensitivity in BOLD (blood oxygenation level dependent) fMRI studies.

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