Surveying the Side-Chain Network Approach to Protein Structure and Dynamics: The SARS-CoV-2 Spike Protein as an Illustrative Case

Keyphrases

• Side Chain 100%
• Protein Dynamics 100%
• Protein Structure 100%
• Network Approach 100%
• Illustrative Case 100%
• Chain Network 100%
• SARS-CoV-2 Spike Protein 100%
• Conformational Change 66%
• Two-state 66%
• Spike Protein 66%
• Illustrative Examples 33%
• Non-covalent 33%
• Human Cells 33%
• Small Changes 33%
• Network Analysis 33%
• Global Change 33%
• Open State 33%
• Chain-based 33%
• Valuable Insight 33%
• Allostery 33%
• Network Theory 33%
• Structural Connectivity 33%
• Global Conformational Changes 33%
• Protein Structure Networks 33%
• Dynamical State 33%
• Strategic Location 33%
• Theory-based Approach 33%
• Connectivity-based 33%
• Network Metrics 33%
• Review Network 33%
• Network-based Analysis 33%
• Physical Concepts 33%
• Optimal Criteria 33%
• Coronavirus Entry 33%
• Drug Design Strategies 33%
• Structural Reorientation 33%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Protein Structure 100%
• Spike 100%
• SARS Coronavirus 100%
• Conformational Change 75%
• Eicosanoid Receptor 25%
• Protein Characterization 25%
• Allosteric Regulation 25%
• Coronavirinae 25%