Abstract
Single-molecule (SM) spectroscopy has been an exciting area of research offering significant promise and hope in the field of sensor development to detect targets at ultra-low levels down to SM resolution. To the experts and developers in the field of surface-enhanced Raman spectroscopy (SERS), this has often been a challenge and a significant opportunity for exploration. Needless to say, the opportunities and excitement of this multidisciplinary area impacts span the fields of physics, chemistry and engineering, along with a significant thrust in applications constituting areas in medicine, biology, environment and agriculture among others. In this review, we will attempt to provide a quick snapshot of the basics of SM-SERS, nanostructures and devices that can enable SM Raman measurement. We will conclude with a discussion on SERS implications in biomedical sciences.
Original language | English (US) |
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Journal | Philosophical Transactions of the Royal Society B: Biological Sciences |
Volume | 368 |
Issue number | 1611 |
DOIs | |
State | Published - Feb 5 2013 |
Externally published | Yes |
Keywords
- Biological sciences
- Hot spot
- Nanotechnology
- Single molecule
- Surface-enhanced Raman spectroscopy
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Agricultural and Biological Sciences