The geniculohypothalamic tract carries visual information from the intergeniculate leaflet to the suprachiasmatic circadian pacemaker. NPY, found in this projection, has been shown to affect the phase of behavioral rhythms and influence photic entrainment. We now demonstrate that NPY, when briefly applied to the geniculate projection sites of rat SCN in vitro, induces permanent phase-shifts in the rhythm of neuronal electrical activity at two separate phases of the circadian cycle.

Original languageEnglish (US)
Pages (from-to)281-286
Number of pages6
JournalBrain Research
Issue number2
StatePublished - Aug 27 1993


  • Brain slice
  • Circadian rhythm
  • Intergeniculate leaflet
  • Neuropeptide Y
  • Pacemaker
  • Rat
  • Suprachiasmatic nuclei

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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