Superoxide anion production by the autoxidation of cytochrome P450cam

S. G. Sligar, J. D. Lipscomb, P. G. Debrunner, I. C. Gunsalus

Research output: Contribution to journalArticlepeer-review


Chemiluminescence occurs on autoxidation of oxygenated ferrous cytochrome P450cam and is abolished by reagents that scavenge free radicals, by superoxide dismutase and singlet oxygen quenchers. We attribute the chemiluminescence to the decay of an excited singlet oxygen which arises from a superoxide anion radical precursor.

Original languageEnglish (US)
Pages (from-to)290-296
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number1
StatePublished - Nov 6 1974

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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