TY - GEN
T1 - Super-Resolution reconstruction of mr image sequences with contrast modeling
AU - Haldar, Justin P.
AU - Hernando, Diego
AU - Liang, Zhi-Pei
PY - 2009
Y1 - 2009
N2 - Quantitative MR imaging experiments (e.g., to measure relaxation and diffusion properties of tissues) often require image sequences with different contrast in each frame. However, high-resolution acquisition of each frame can lead to prohibitively long experiments. In this work, we investigate the possibility of utilizing a parametric contrast model to synthesize high-resolution information. Theoretical analysis and empirical evidence indicates that this kind of super-resolution can be possible, though robustness is dependent on a number of factors (e.g., the contrast model and the experiment design). In particular, it is found that conventional low-frequency sampling leads to significant information loss, but that alternative experiments can overcome this limitation. Experimental results are shown in the context of T* 2 relaxation mapping.
AB - Quantitative MR imaging experiments (e.g., to measure relaxation and diffusion properties of tissues) often require image sequences with different contrast in each frame. However, high-resolution acquisition of each frame can lead to prohibitively long experiments. In this work, we investigate the possibility of utilizing a parametric contrast model to synthesize high-resolution information. Theoretical analysis and empirical evidence indicates that this kind of super-resolution can be possible, though robustness is dependent on a number of factors (e.g., the contrast model and the experiment design). In particular, it is found that conventional low-frequency sampling leads to significant information loss, but that alternative experiments can overcome this limitation. Experimental results are shown in the context of T* 2 relaxation mapping.
KW - Magnetic resonance imaging
KW - Parameter estimation
KW - Sequence estimation
UR - http://www.scopus.com/inward/record.url?scp=70449344646&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70449344646&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2009.5193035
DO - 10.1109/ISBI.2009.5193035
M3 - Conference contribution
AN - SCOPUS:70449344646
SN - 9781424439324
T3 - Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
SP - 266
EP - 269
BT - Proceedings - 2009 IEEE International Symposium on Biomedical Imaging
T2 - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Y2 - 28 June 2009 through 1 July 2009
ER -