Super-resolution localization microscopy: Toward high throughput, high quality, and low cost

Hongqiang Ma, Yang Liu

Research output: Contribution to journalArticlepeer-review

Abstract

After nearly 15 years since its initial debut, super-resolution localization microscopy that surpasses the diffraction-limited resolution barrier of optical microscopy has rapidly gotten out of the ivory tower and entered a new phase to address various challenging biomedical questions. Recent advances in this technology greatly increased the imaging throughput, improved the imaging quality, simplified the sample preparation, and reduced the system cost, making this technology suitable for routine biomedical research. We will provide our perspective on the recent technical advances and their implications in serving the community of biomedical research.

Original languageEnglish (US)
Article number060902
JournalAPL Photonics
Volume5
Issue number6
DOIs
StatePublished - 2020
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Computer Networks and Communications

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