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Substrate control in stereoselective lanthionine biosynthesis
Weixin Tang
, Gonzalo Jiménez-Osés
, K. N. Houk
,
Wilfred A. Van Der Donk
Chemistry
Bioengineering
Biomedical and Translational Sciences
Carl R. Woese Institute for Genomic Biology
Research output
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peer-review
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Keyphrases
Stereoselectivity
100%
Lanthionine
100%
Substrate Control
100%
Cysteine
50%
Highly Selective
50%
Single-point mutation
50%
Enzyme Catalysis
50%
Rare Example
50%
Amino Acid Sequence
50%
Michael Addition
50%
Transition State
50%
Natural Products
50%
Stereochemical Hypothesis
50%
Quantum Mechanical Calculations
50%
Cyclization
50%
Thioether
50%
Peptide Substrate
50%
Highly Stereoselective
50%
Synthetase
50%
Face Selectivity
50%
Anti-addition
50%
Lanthipeptide
50%
Si-face
50%
Enzymatic Modification
50%
Conformational Restraint
50%
Biochemistry, Genetics and Molecular Biology
Anabolism
100%
Enzyme
100%
Lanthionine
100%
Conformation
33%
Cross-Link
33%
Peptide Sequence
33%
Point Mutation
33%
Stereoselectivity
33%
Thioether
33%
Cysteine
33%
Chemistry
Michael Reaction
100%
Lanthionine
100%
Transition State
50%
Stereoselectivity
50%
Stereoselective Catalyst
50%
Natural Product
50%
Amino Acid Sequence
50%
Cysteine
50%