Structure of the transition state of gating in the acetylcholine receptor channel pore: A Φ-value analysis

Keyphrases

• Acetylcholine 16%
• Acetylcholine Receptor (AChR) 100%
• Alpha Value 100%
• Asynchronously 16%
• Binding Site 16%
• Channel Closing 16%
• Channel Opening 16%
• Channel Pore 100%
• Closed Conformation 16%
• Closed State 16%
• Conformational Change 33%
• Equilibrium Constant 16%
• Gating Mechanism 16%
• Linear Free Energy Relationships 33%
• Lining Segment 16%
• M2 Segment 33%
• Molecular Events 16%
• Open Conformation 16%
• Open State 16%
• Physical Interpretation 16%
• Point mutation 16%
• Pore Lining 16%
• Primary Sequence 16%
• Single Channel 16%
• State Value 33%
• Transition State 100%
• Transmembrane Segment 16%
• Two-point 16%

Biochemistry, Genetics and Molecular Biology

• Acetylcholine 33%
• Acetylcholine Receptor 100%
• Binding Site 33%
• Conformation 33%
• Conformational Change 66%
• Equilibrium Constant 33%
• Point Mutation 33%

Neuroscience

• Acetylcholine 33%
• Binding Site 33%
• Cholinergic Receptor 100%
• Point Mutation 33%