Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor

Ryan E. Cobb, Brian Bae, Zhi Li, Matthew A. Desieno, Satish K. Nair, Huimin Zhao

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