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Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis
Bo Li
, John Paul J. Yu
, Joseph S. Brunzelle
, Gert N. Moll
,
Wilfred A. Van Der Donk
,
Satish K. Nair
Chemistry
Carl R. Woese Institute for Genomic Biology
Biochemistry
School of Molecular and Cellular Biology
Materials Research Lab
Bioengineering
Biomedical and Translational Sciences
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Keyphrases
Nisin
100%
Lantibiotics
100%
Cyclase
100%
Cysteine
50%
X-ray Crystal Structure
50%
Multi-enzyme
50%
In Vitro Reconstitution
50%
Antimicrobial Peptides
50%
Cyclic Thioethers
50%
Protein Substrate
50%
Farnesyltransferase
50%
Human Homolog
50%
Substrate Activation
50%
Cyclization Processes
50%
Food Preservatives
50%
Biochemistry, Genetics and Molecular Biology
Anabolism
100%
Enzyme
100%
Nisin
100%
Cyclase
100%
Lantibiotic
100%
Crystal Structure
50%
Antimicrobial Peptides
50%
Thioether
50%
Farnesyltransferase
50%
Cysteine
50%