TY - JOUR
T1 - Structure and function of thebc-complex ofRhodobacter sphaeroides
AU - Crofts, Antony
AU - Hacker, Beth
AU - Barquera, Blanca
AU - Yun, Chang Hyon
AU - Gennis, Robert
PY - 1992
Y1 - 1992
N2 - The ubiquinol: cytochromec2 oxidoreductase (bc-complex) ofRhodobacter sphaeroides has three main subunits, which bear the prosthetic groups, and contribute to three catalytic sites and internal electron transfer pathways which define the modified Q-cycle mechanism. In this paper, we report on progress in modelling the structure of thebc-complex, and experiments using site directed mutagenesis and biophysical assay to probe the structural and function consequences of specific modifications to these subunits.
AB - The ubiquinol: cytochromec2 oxidoreductase (bc-complex) ofRhodobacter sphaeroides has three main subunits, which bear the prosthetic groups, and contribute to three catalytic sites and internal electron transfer pathways which define the modified Q-cycle mechanism. In this paper, we report on progress in modelling the structure of thebc-complex, and experiments using site directed mutagenesis and biophysical assay to probe the structural and function consequences of specific modifications to these subunits.
KW - Cytochromebc-complex
KW - Rb sphaeroides
KW - Site-directed mutagenesis
KW - Ubiquinol cytochromec oxidoreductase
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U2 - 10.1016/0005-2728(92)90202-D
DO - 10.1016/0005-2728(92)90202-D
M3 - Article
C2 - 1321665
AN - SCOPUS:0026694283
SN - 0005-2728
VL - 1101
SP - 162
EP - 165
JO - Biochimica et Biophysica Acta - Bioenergetics
JF - Biochimica et Biophysica Acta - Bioenergetics
IS - 2
ER -