The ubiquinol: cytochromec2 oxidoreductase (bc-complex) ofRhodobacter sphaeroides has three main subunits, which bear the prosthetic groups, and contribute to three catalytic sites and internal electron transfer pathways which define the modified Q-cycle mechanism. In this paper, we report on progress in modelling the structure of thebc-complex, and experiments using site directed mutagenesis and biophysical assay to probe the structural and function consequences of specific modifications to these subunits.
- Rb sphaeroides
- Site-directed mutagenesis
- Ubiquinol cytochromec oxidoreductase
ASJC Scopus subject areas
- Cell Biology