Structure-activity relationships of the phosphonate antibiotic dehydrophos

Michael Kuemin, Wilfred A. Van Der Donk

Research output: Contribution to journalArticlepeer-review

Abstract

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

Original languageEnglish (US)
Pages (from-to)7694-7696
Number of pages3
JournalChemical Communications
Volume46
Issue number41
DOIs
StatePublished - Nov 7 2010

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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