TY - JOUR
T1 - Structural DNA nanotechnology
T2 - 4th International Conference on Unconventional Computation, UC 2005
AU - Sha, Ruojie
AU - Zhang, Xiaoping
AU - Liao, Shiping
AU - Constantinou, Pamela E.
AU - Ding, Baoquan
AU - Wang, Tong
AU - Garibotti, Alejandra V.
AU - Zhong, Hong
AU - Israel, Lisa B.
AU - Wang, Xing
AU - Wu, Gang
AU - Chakraborty, Banani
AU - Chen, Junghuei
AU - Zhang, Yuwen
AU - Yan, Hao
AU - Shen, Zhiyong
AU - Shen, Wanqiu
AU - Sa-Ardyen, Phiset
AU - Kopatsch, Jens
AU - Zheng, Jiwen
AU - Lukeman, Philip S.
AU - Sherman, William B.
AU - Mao, Chengde
AU - Jonoska, Natasha
AU - Seeman, Nadrian C.
PY - 2005/10/31
Y1 - 2005/10/31
N2 - Structural DNA nanotechnology entails the construction of objects, lattices and devices from branched DNA molecules. Branched DNA molecules open the way for the construction of a variety of N-connected motifs. These motifs can be joined by cohesive interactions to produce larger constructs in a bottom-up approach to nanoconstruction. The first objects produced by this approach were stick polyhedra and topological targets, such as knots and Borromean rings. These were followed by periodic arrays with programmable patterns. It is possible to exploit DNA structural transitions and sequence-specific binding to produce a variety of DNA nanomechanical devices, which include a bipedal walker and a machine that emulates the translational capabilities of the ribosome. Much of the promise of this methodology involves the use of DNA to scaffold other materials, such as biological macromolecules, nanoelectronic components, and polymers. These systems are designed to lead to improvements in crystallography, computation and the production of diverse and exotic materials. Branched DNA can be used to emulate Wang tiles, and it can be used to construct arbitrary irregular graphs and to address their colorability.
AB - Structural DNA nanotechnology entails the construction of objects, lattices and devices from branched DNA molecules. Branched DNA molecules open the way for the construction of a variety of N-connected motifs. These motifs can be joined by cohesive interactions to produce larger constructs in a bottom-up approach to nanoconstruction. The first objects produced by this approach were stick polyhedra and topological targets, such as knots and Borromean rings. These were followed by periodic arrays with programmable patterns. It is possible to exploit DNA structural transitions and sequence-specific binding to produce a variety of DNA nanomechanical devices, which include a bipedal walker and a machine that emulates the translational capabilities of the ribosome. Much of the promise of this methodology involves the use of DNA to scaffold other materials, such as biological macromolecules, nanoelectronic components, and polymers. These systems are designed to lead to improvements in crystallography, computation and the production of diverse and exotic materials. Branched DNA can be used to emulate Wang tiles, and it can be used to construct arbitrary irregular graphs and to address their colorability.
KW - Bottom-Up Nanoscale Construction
KW - DNA Sequence Design
KW - Nanorobotics
KW - Nanoscale DNA Objects
KW - Nanoscale Pattern Design
KW - Unusual DNA Motifs
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U2 - 10.1007/11560319_4
DO - 10.1007/11560319_4
M3 - Conference article
AN - SCOPUS:27144496667
SN - 0302-9743
VL - 3699
SP - 20
EP - 31
JO - Lecture Notes in Computer Science
JF - Lecture Notes in Computer Science
Y2 - 3 October 2005 through 7 October 2005
ER -