Strontium Regulates the Proliferation and Differentiation of Isolated Primary Bovine Chondrocytes via the TGFβ/SMAD Pathway

Keyphrases

• Transforming Growth Factor-β 100%
• Smad Signaling Pathway 100%
• Bovine Chondrocytes 100%
• Strontium 100%
• Phosphorylation 38%
• SB505124 30%
• TGF-1 23%
• Incubation 23%
• Chondrocytes 23%
• Smad3 23%
• Collagen Type 1 15%
• Aggrecan 15%
• Smad1 15%
• COL2A1 15%
• Activin Receptor-like Kinase 5 15%
• Ribonuclease 7%
• Sodium Chloride 7%
• Quantitative PCR 7%
• Cell number 7%
• Western Blot 7%
• Flow Cytometry 7%
• Alkaline Phosphatase 7%
• Protein Level 7%
• MRNA Level 7%
• Livestock 7%
• Sigma Phase 7%
• Overall Effect 7%
• Growth Factor Signaling 7%
• Dairy Cow 7%
• Holstein Cows 7%
• Cell Cycle Activity 7%
• Euthanasia 7%
• Experimental Tools 7%
• One-way ANOVA 7%
• Primary Chondrocytes 7%
• COL10A1 7%
• Proliferation Index 7%
• Patellar Cartilage 7%
• ALK1 7%
• GraphPad Prism 7%
• Secreted Phosphoprotein 1 (SPP1) 7%

Pharmacology, Toxicology and Pharmaceutical Science

• Cancer Growth Factor 100%
• Messenger RNA 100%
• Collagen Type 1 66%
• Aggrecan 66%
• Transforming Growth Factor Beta Receptor 1 66%
• Buffer 33%
• Ribonuclease 33%
• Flow Cytometry 33%
• Alkaline Phosphatase 33%
• Osteopontin 33%
• Western Blot 33%
• Cow 33%

Veterinary Science and Veterinary Medicine

• Chondrocyte 100%
• Cancer Growth Factor 100%
• Alkaline Phosphatase 20%
• Dairy Cows 20%
• Quantitative Reverse Transcription Polymerase Chain Reaction 20%