Abstract
All four stereoisomers of Δ9-tetrahydrocannabinol (Δ9-THC) were synthesized in concise fashion using stereodivergent dual catalysis. Thus, following identical synthetic sequences and applying identical reaction conditions to the same set of starting materials, selective access to the four stereoisomers of THC was achieved in five steps.
Original language | English (US) |
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Pages (from-to) | 13898-13901 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 53 |
Issue number | 50 |
DOIs | |
State | Published - Oct 10 2014 |
Externally published | Yes |
Keywords
- Dual catalysis
- Stereodivergent synthesis
- Tetrahydrocannabinol
- Total synthesis
ASJC Scopus subject areas
- Catalysis
- General Chemistry