Statistical signal processing for quantitative assessment of pulsed terahertz imaging of human breast tumors

Tyler Bowman, Tanny Chavez, Kamrul Khan, Avishek Chakraborty, Jingxian Wu, Keith Bailey, Magda El-Shenawee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents utilization of pulsed terahertz imaging to detect and assess the margins of excised human breast tumors. The freshly excised bulk tissue and the block of the same tissue fixed in formalin and embedded in paraffin (FFPE) are scanned using the reflection imaging module. The results show that while the THz images of block tissue demonstrate strong contrast between cancerous and fibroglandular (normal) regions, the contrast is less strong in the images of freshly excised bulk tissue. This could be due to remains of blood and presence of air bubbles in the specimen. To validate the THz images, we develop signal processing and statistical data analysis techniques based on image morphing and Bayesian modeling. The results are quantified in the form of receiver operating characteristic (ROC) curves.

Original languageEnglish (US)
Title of host publication2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781509060481
DOIs
StatePublished - Oct 12 2017
Externally publishedYes
Event42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017 - Cancun, Quintana Roo, Mexico
Duration: Aug 27 2017Sep 1 2017

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
Country/TerritoryMexico
CityCancun, Quintana Roo
Period8/27/179/1/17

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Electrical and Electronic Engineering

Fingerprint

Dive into the research topics of 'Statistical signal processing for quantitative assessment of pulsed terahertz imaging of human breast tumors'. Together they form a unique fingerprint.

Cite this