Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity

Chandy C. John, Micah Niermann, Bazak Sharon, Marnie L. Peterson, David M. Kranz, Patrick M. Schlievert

Research output: Contribution to journalArticle

Abstract

Staphylococcal toxic shock syndrome (TSS) has rarely been reported without rash and desquamation. This study describes a patient who met all criteria for TSS except erythroderma and desquamation. The associated staphylococcal superantigen was enterotoxin B. We demonstrate that erythroderma depends on preexisting T cell hypersensitivity amplified by superantigenicity.

Original languageEnglish (US)
Pages (from-to)1893-1896
Number of pages4
JournalClinical Infectious Diseases
Volume49
Issue number12
DOIs
StatePublished - Dec 1 2009
Externally publishedYes

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Exfoliative Dermatitis
Septic Shock
Hypersensitivity
Superantigens
Enterotoxins
Exanthema
T-Lymphocytes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. / John, Chandy C.; Niermann, Micah; Sharon, Bazak; Peterson, Marnie L.; Kranz, David M.; Schlievert, Patrick M.

In: Clinical Infectious Diseases, Vol. 49, No. 12, 01.12.2009, p. 1893-1896.

Research output: Contribution to journalArticle

John, Chandy C. ; Niermann, Micah ; Sharon, Bazak ; Peterson, Marnie L. ; Kranz, David M. ; Schlievert, Patrick M. / Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. In: Clinical Infectious Diseases. 2009 ; Vol. 49, No. 12. pp. 1893-1896.
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