SprB Is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4

Supreet Saini, Christopher V. Rao

Research output: Contribution to journalArticlepeer-review

Abstract

Salmonella pathogenicity island 1 (SPI1) and SPI4 have previously been shown to be jointly regulated. We report that SPI1 and SPI4 gene expression is linked through a transcriptional activator, SprB, encoded within SPI1 and regulated by HilA. SprB directly activates SPI4 gene expression and weakly represses SPI1 gene expression through HilD.

Original languageEnglish (US)
Pages (from-to)2459-2462
Number of pages4
JournalJournal of bacteriology
Volume192
Issue number9
DOIs
StatePublished - May 2010

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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