Salmonella pathogenicity island 1 (SPI1) and SPI4 have previously been shown to be jointly regulated. We report that SPI1 and SPI4 gene expression is linked through a transcriptional activator, SprB, encoded within SPI1 and regulated by HilA. SprB directly activates SPI4 gene expression and weakly represses SPI1 gene expression through HilD.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of bacteriology|
|State||Published - May 2010|
ASJC Scopus subject areas
- Molecular Biology