The speotroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells.

Original languageEnglish (US)
Pages (from-to)1079-1081
Number of pages3
JournalOptics Letters
Issue number8
StatePublished - Apr 15 2006

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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