Specificity of regional brain activity in anxiety types during emotion processing

Anna S. Engels, Wendy Heller, Aprajita Mohanty, John D. Herrington, Marie T. Banich, Andrew G. Webb, Gregory A. Miller

Research output: Contribution to journalArticle

Abstract

The present study tested the hypothesis that anxious apprehension involves more left- than right-hemisphere activity and that anxious arousal is associated with the opposite pattern. Behavioral and fMRI responses to threat stimuli in an emotional Stroop task were examined in nonpatient groups reporting anxious apprehension, anxious arousal, or neither. Reaction times were longer for negative than for neutral words. As predicted, brain activation distinguished anxious groups in a left inferior frontal region associated with speech production and in a right-hemisphere inferior temporal area. Addressing a second hypothesis about left-frontal involvement in emotion, distinct left frontal regions were associated with anxious apprehension versus processing of positive information. Results support the proposed distinction between the two types of anxiety and resolve an inconsistency about the role of left-frontal activation in emotion and psychopathology.

Original languageEnglish (US)
Pages (from-to)352-363
Number of pages12
JournalPsychophysiology
Volume44
Issue number3
DOIs
StatePublished - May 1 2007

Fingerprint

Arousal
Emotions
Anxiety
Brain
Psychopathology
Automatic Data Processing
Reaction Time
Magnetic Resonance Imaging

Keywords

  • Anxiety
  • Anxious apprehension
  • Anxious arousal
  • Emotion
  • Stroop
  • fMRI

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Neurology
  • Endocrine and Autonomic Systems
  • Developmental Neuroscience
  • Cognitive Neuroscience
  • Biological Psychiatry

Cite this

Engels, A. S., Heller, W., Mohanty, A., Herrington, J. D., Banich, M. T., Webb, A. G., & Miller, G. A. (2007). Specificity of regional brain activity in anxiety types during emotion processing. Psychophysiology, 44(3), 352-363. https://doi.org/10.1111/j.1469-8986.2007.00518.x

Specificity of regional brain activity in anxiety types during emotion processing. / Engels, Anna S.; Heller, Wendy; Mohanty, Aprajita; Herrington, John D.; Banich, Marie T.; Webb, Andrew G.; Miller, Gregory A.

In: Psychophysiology, Vol. 44, No. 3, 01.05.2007, p. 352-363.

Research output: Contribution to journalArticle

Engels, AS, Heller, W, Mohanty, A, Herrington, JD, Banich, MT, Webb, AG & Miller, GA 2007, 'Specificity of regional brain activity in anxiety types during emotion processing', Psychophysiology, vol. 44, no. 3, pp. 352-363. https://doi.org/10.1111/j.1469-8986.2007.00518.x
Engels, Anna S. ; Heller, Wendy ; Mohanty, Aprajita ; Herrington, John D. ; Banich, Marie T. ; Webb, Andrew G. ; Miller, Gregory A. / Specificity of regional brain activity in anxiety types during emotion processing. In: Psychophysiology. 2007 ; Vol. 44, No. 3. pp. 352-363.
@article{c1ecf40617264f57891076d74fb5af44,
title = "Specificity of regional brain activity in anxiety types during emotion processing",
abstract = "The present study tested the hypothesis that anxious apprehension involves more left- than right-hemisphere activity and that anxious arousal is associated with the opposite pattern. Behavioral and fMRI responses to threat stimuli in an emotional Stroop task were examined in nonpatient groups reporting anxious apprehension, anxious arousal, or neither. Reaction times were longer for negative than for neutral words. As predicted, brain activation distinguished anxious groups in a left inferior frontal region associated with speech production and in a right-hemisphere inferior temporal area. Addressing a second hypothesis about left-frontal involvement in emotion, distinct left frontal regions were associated with anxious apprehension versus processing of positive information. Results support the proposed distinction between the two types of anxiety and resolve an inconsistency about the role of left-frontal activation in emotion and psychopathology.",
keywords = "Anxiety, Anxious apprehension, Anxious arousal, Emotion, Stroop, fMRI",
author = "Engels, {Anna S.} and Wendy Heller and Aprajita Mohanty and Herrington, {John D.} and Banich, {Marie T.} and Webb, {Andrew G.} and Miller, {Gregory A.}",
year = "2007",
month = "5",
day = "1",
doi = "10.1111/j.1469-8986.2007.00518.x",
language = "English (US)",
volume = "44",
pages = "352--363",
journal = "Psychophysiology",
issn = "0048-5772",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Specificity of regional brain activity in anxiety types during emotion processing

AU - Engels, Anna S.

AU - Heller, Wendy

AU - Mohanty, Aprajita

AU - Herrington, John D.

AU - Banich, Marie T.

AU - Webb, Andrew G.

AU - Miller, Gregory A.

PY - 2007/5/1

Y1 - 2007/5/1

N2 - The present study tested the hypothesis that anxious apprehension involves more left- than right-hemisphere activity and that anxious arousal is associated with the opposite pattern. Behavioral and fMRI responses to threat stimuli in an emotional Stroop task were examined in nonpatient groups reporting anxious apprehension, anxious arousal, or neither. Reaction times were longer for negative than for neutral words. As predicted, brain activation distinguished anxious groups in a left inferior frontal region associated with speech production and in a right-hemisphere inferior temporal area. Addressing a second hypothesis about left-frontal involvement in emotion, distinct left frontal regions were associated with anxious apprehension versus processing of positive information. Results support the proposed distinction between the two types of anxiety and resolve an inconsistency about the role of left-frontal activation in emotion and psychopathology.

AB - The present study tested the hypothesis that anxious apprehension involves more left- than right-hemisphere activity and that anxious arousal is associated with the opposite pattern. Behavioral and fMRI responses to threat stimuli in an emotional Stroop task were examined in nonpatient groups reporting anxious apprehension, anxious arousal, or neither. Reaction times were longer for negative than for neutral words. As predicted, brain activation distinguished anxious groups in a left inferior frontal region associated with speech production and in a right-hemisphere inferior temporal area. Addressing a second hypothesis about left-frontal involvement in emotion, distinct left frontal regions were associated with anxious apprehension versus processing of positive information. Results support the proposed distinction between the two types of anxiety and resolve an inconsistency about the role of left-frontal activation in emotion and psychopathology.

KW - Anxiety

KW - Anxious apprehension

KW - Anxious arousal

KW - Emotion

KW - Stroop

KW - fMRI

UR - http://www.scopus.com/inward/record.url?scp=34247140658&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247140658&partnerID=8YFLogxK

U2 - 10.1111/j.1469-8986.2007.00518.x

DO - 10.1111/j.1469-8986.2007.00518.x

M3 - Article

C2 - 17433094

AN - SCOPUS:34247140658

VL - 44

SP - 352

EP - 363

JO - Psychophysiology

JF - Psychophysiology

SN - 0048-5772

IS - 3

ER -