Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

Amr A. Abdeen, Junmin Lee, Samuel H. Mo, Kristopher A. Kilian

Research output: Contribution to journalArticle

Abstract

The spatiotemporal coordination of angiogenesis in synthetic materials is important for mimicking natural tissue morphogenesis. Here we report patterned hydrogel encapsulation of mesenchymal stem cells to direct endothelial tubulogenesis in co-culture. Tubulogenesis occurs preferentially over MSC patterns, suggesting this strategy may prove useful in guiding the design of heterotypic engineered tissues.

Original languageEnglish (US)
Pages (from-to)7896-7898
Number of pages3
JournalJournal of Materials Chemistry B
Volume3
Issue number40
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

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