Sources of PM2.5 with high oxidative potential linked to health effects

Josephine Bates, Rodney J. Weber, Ting Fang, James A. Mulholland, Armistead Russell, Joseph Abrams, Mitchel Klein, Matthew J. Strickland, Stefanie E. Sarnat, Howard H. Chang, Paige E. Tolbert, Vishal Verma

Research output: Contribution to journalConference articlepeer-review


The use of a novel measure of reactive oxygen species-generating potential, or oxidative potential (OP), of water-soluble PM2.5 as a health indicator was studied. A cellular dithiothreitol (DTT) assay was chosen to measure OP. An association between PM2.5 sources with high oxidative potential (OPDTT) and asthma/wheeze and congestive heart failure in the Atlanta area. The sources that contributed most to the OPDTT of PM2.5 include controlled burns, light-duty gasoline vehicles, and heavy-duty diesel vehicles, respectively.The health links with OPDTT suggest that reductions in vehicle and controlled burn emissions may be effective in preventing emergency department visits associated with asthma and wheezing attacks and congestive heart failure. This is an abstract of a paper presented at the A&WMA's 109th Annual Conference & Exhibition (New Orleans, LA 6/20-23/2016).

Original languageEnglish (US)
Pages (from-to)1528-1532
Number of pages5
JournalProceedings of the Air and Waste Management Association's Annual Conference and Exhibition, AWMA
StatePublished - 2016
Event109th Air and Waste Management Association Annual Conference and Exhibition: Unmasking the Industrial Renaissance, ACE 2016 - New Orleans, United States
Duration: Jun 20 2016Jun 23 2016


  • Air pollution
  • DTT assay
  • Reactive oxygen species
  • Source apportionment

ASJC Scopus subject areas

  • Environmental Science(all)
  • Energy(all)


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