Sources of PM2.5 with high oxidative potential linked to health effects

Josephine Bates; Rodney J. Weber; Ting Fang; James A. Mulholland; Armistead Russell; Joseph Abrams; Mitchel Klein; Matthew J. Strickland; Stefanie E. Sarnat; Howard H. Chang; Paige E. Tolbert; Vishal Verma

Sources of PM_2.5 with high oxidative potential linked to health effects

Josephine Bates, Rodney J. Weber, Ting Fang, James A. Mulholland, Armistead Russell, Joseph Abrams, Mitchel Klein, Matthew J. Strickland, Stefanie E. Sarnat, Howard H. Chang, Paige E. Tolbert, Vishal Verma

Civil and Environmental Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

The use of a novel measure of reactive oxygen species-generating potential, or oxidative potential (OP), of water-soluble PM_2.5 as a health indicator was studied. A cellular dithiothreitol (DTT) assay was chosen to measure OP. An association between PM_2.5 sources with high oxidative potential (OP_DTT) and asthma/wheeze and congestive heart failure in the Atlanta area. The sources that contributed most to the OP_DTT of PM_2.5 include controlled burns, light-duty gasoline vehicles, and heavy-duty diesel vehicles, respectively.The health links with OP_DTT suggest that reductions in vehicle and controlled burn emissions may be effective in preventing emergency department visits associated with asthma and wheezing attacks and congestive heart failure. This is an abstract of a paper presented at the A&WMA's 109th Annual Conference & Exhibition (New Orleans, LA 6/20-23/2016).

Original language	English (US)
Pages (from-to)	1528-1532
Number of pages	5
Journal	Proceedings of the Air and Waste Management Association's Annual Conference and Exhibition, AWMA
Volume	2
State	Published - 2016
Event	109th Air and Waste Management Association Annual Conference and Exhibition: Unmasking the Industrial Renaissance, ACE 2016 - New Orleans, United States Duration: Jun 20 2016 → Jun 23 2016

Keywords

Air pollution
DTT assay
Reactive oxygen species
Source apportionment

ASJC Scopus subject areas

Environmental Science(all)
Energy(all)

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title = "Sources of PM2.5 with high oxidative potential linked to health effects",

abstract = "The use of a novel measure of reactive oxygen species-generating potential, or oxidative potential (OP), of water-soluble PM2.5 as a health indicator was studied. A cellular dithiothreitol (DTT) assay was chosen to measure OP. An association between PM2.5 sources with high oxidative potential (OPDTT) and asthma/wheeze and congestive heart failure in the Atlanta area. The sources that contributed most to the OPDTT of PM2.5 include controlled burns, light-duty gasoline vehicles, and heavy-duty diesel vehicles, respectively.The health links with OPDTT suggest that reductions in vehicle and controlled burn emissions may be effective in preventing emergency department visits associated with asthma and wheezing attacks and congestive heart failure. This is an abstract of a paper presented at the A&WMA's 109th Annual Conference & Exhibition (New Orleans, LA 6/20-23/2016).",

keywords = "Air pollution, DTT assay, Reactive oxygen species, Source apportionment",

author = "Josephine Bates and Weber, {Rodney J.} and Ting Fang and Mulholland, {James A.} and Armistead Russell and Joseph Abrams and Mitchel Klein and Strickland, {Matthew J.} and Sarnat, {Stefanie E.} and Chang, {Howard H.} and Tolbert, {Paige E.} and Vishal Verma",

note = "Copyright: Copyright 2017 Elsevier B.V., All rights reserved.; 109th Air and Waste Management Association Annual Conference and Exhibition: Unmasking the Industrial Renaissance, ACE 2016 ; Conference date: 20-06-2016 Through 23-06-2016",

year = "2016",

language = "English (US)",

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AU - Bates, Josephine

AU - Weber, Rodney J.

AU - Fang, Ting

AU - Mulholland, James A.

AU - Russell, Armistead

AU - Abrams, Joseph

AU - Klein, Mitchel

AU - Strickland, Matthew J.

AU - Sarnat, Stefanie E.

AU - Chang, Howard H.

AU - Tolbert, Paige E.

AU - Verma, Vishal

PY - 2016

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N2 - The use of a novel measure of reactive oxygen species-generating potential, or oxidative potential (OP), of water-soluble PM2.5 as a health indicator was studied. A cellular dithiothreitol (DTT) assay was chosen to measure OP. An association between PM2.5 sources with high oxidative potential (OPDTT) and asthma/wheeze and congestive heart failure in the Atlanta area. The sources that contributed most to the OPDTT of PM2.5 include controlled burns, light-duty gasoline vehicles, and heavy-duty diesel vehicles, respectively.The health links with OPDTT suggest that reductions in vehicle and controlled burn emissions may be effective in preventing emergency department visits associated with asthma and wheezing attacks and congestive heart failure. This is an abstract of a paper presented at the A&WMA's 109th Annual Conference & Exhibition (New Orleans, LA 6/20-23/2016).

AB - The use of a novel measure of reactive oxygen species-generating potential, or oxidative potential (OP), of water-soluble PM2.5 as a health indicator was studied. A cellular dithiothreitol (DTT) assay was chosen to measure OP. An association between PM2.5 sources with high oxidative potential (OPDTT) and asthma/wheeze and congestive heart failure in the Atlanta area. The sources that contributed most to the OPDTT of PM2.5 include controlled burns, light-duty gasoline vehicles, and heavy-duty diesel vehicles, respectively.The health links with OPDTT suggest that reductions in vehicle and controlled burn emissions may be effective in preventing emergency department visits associated with asthma and wheezing attacks and congestive heart failure. This is an abstract of a paper presented at the A&WMA's 109th Annual Conference & Exhibition (New Orleans, LA 6/20-23/2016).

KW - Air pollution

KW - DTT assay

KW - Reactive oxygen species

KW - Source apportionment

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