In solution, biopolymers commonly fold into well-defined three- dimensional structures, but only recently has analogous behavior been explored in synthetic chain molecules. An aromatic hydrocarbon backbone is described that spontaneously acquires a stable helical conformation having a large cavity. The chain does not form intramolecular hydrogen bonds, and solvophobic interactions drive the folding transition, which is sensitive to chain length, solvent quality, and temperature.

Original languageEnglish (US)
Pages (from-to)1793-1796
Number of pages4
Issue number5333
StatePublished - Sep 19 1997

ASJC Scopus subject areas

  • General


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