TY - JOUR
T1 - Small Portable Interchangeable Imager of Fluorescence for Fluorescence Guided Surgery and Research
AU - Okusanya, Olugbenga T.
AU - Madajewski, Brian
AU - Segal, Erin
AU - Judy, Brendan F.
AU - Venegas, Ollin G.
AU - Judy, Ryan P.
AU - Quatromoni, Jon G.
AU - Wang, May D.
AU - Nie, Shuming
AU - Singhal, Sunil
N1 - Publisher Copyright:
© 2014, © The Author(s) 2014.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Fluorescence guided surgery (FGS) is a developing field of surgical and oncologic research. Practically, FGS has shown useful applications in urologic surgery, benign biliary surgery, colorectal cancer liver metastasis resection, and ovarian cancer debulking. Most notably in in cancer surgery, FGS allows for the clear delineation of cancerous tissue from benign tissue. FGS requires the utilization of a fluorescent contrast agent and an intraoperative fluorescence imaging device (IFID). Currently available IFIDs are expensive, unable to work with multiple fluorophores, and can be cumbersome. This study aims to describe the development and utility of a small, cost-efficient, and interchangeable IFID made from commercially available components. Extensive research was done to design and construct a light-weight, portable, and cost-effective IFID. We researched the capabilities, size, and cost of several camera types and eventually decided on a near-infrared (NIR) charged couple device (CCD) camera for its overall profile. The small portable interchangeable imager of fluorescence (SPIIF) is a “scout” IFID system for FGS. The main components of the SPIIF are a NIR CCD camera with an articulating light filter. These components and a LED light source with an attached heat sink are mounted on a small metal platform. The system is connected to a laptop by a USB 2.0 cable.
AB - Fluorescence guided surgery (FGS) is a developing field of surgical and oncologic research. Practically, FGS has shown useful applications in urologic surgery, benign biliary surgery, colorectal cancer liver metastasis resection, and ovarian cancer debulking. Most notably in in cancer surgery, FGS allows for the clear delineation of cancerous tissue from benign tissue. FGS requires the utilization of a fluorescent contrast agent and an intraoperative fluorescence imaging device (IFID). Currently available IFIDs are expensive, unable to work with multiple fluorophores, and can be cumbersome. This study aims to describe the development and utility of a small, cost-efficient, and interchangeable IFID made from commercially available components. Extensive research was done to design and construct a light-weight, portable, and cost-effective IFID. We researched the capabilities, size, and cost of several camera types and eventually decided on a near-infrared (NIR) charged couple device (CCD) camera for its overall profile. The small portable interchangeable imager of fluorescence (SPIIF) is a “scout” IFID system for FGS. The main components of the SPIIF are a NIR CCD camera with an articulating light filter. These components and a LED light source with an attached heat sink are mounted on a small metal platform. The system is connected to a laptop by a USB 2.0 cable.
KW - Fluorescence guided surgery
KW - Indocyanine green
KW - Intraoperative imaging
KW - Near infrared
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UR - http://www.scopus.com/inward/citedby.url?scp=84941766496&partnerID=8YFLogxK
U2 - 10.7785/tcrt.2012.500400
DO - 10.7785/tcrt.2012.500400
M3 - Article
C2 - 24354756
AN - SCOPUS:84941766496
SN - 1533-0346
VL - 14
SP - 213
EP - 220
JO - Technology in Cancer Research and Treatment
JF - Technology in Cancer Research and Treatment
IS - 2
ER -