Small-Animal SPECT, SPECT/CT, and SPECT/MRI

Ling Jian Meng, Neal H. Clinthorne

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this chapter, we provide an overview of small-animal single-photon emission computed tomography (SPECT) applications and instrumentation. To reflect the recent expansion of both research and commercial activity in SPECT, SPECT/CT, and SPECT/MRI devices for small animals, the chapter has been organized to provide some history and a basic overview of applications and commercial instruments followed by a description of basic hardware and image formation methods in SPECT. Design trends in small-animal SPECT devices are then discussed, and the chapter concludes with a brief discussion of future directions in the field.

Original languageEnglish (US)
Title of host publicationMolecular Imaging
Subtitle of host publicationPrinciples and Practice
PublisherElsevier
Pages65-87
Number of pages23
ISBN (Electronic)9780128163863
ISBN (Print)9780128163870
DOIs
StatePublished - Jan 1 2021

Keywords

  • Collimation aperture
  • Maximum likelihood reconstruction
  • Multimodality imaging
  • Radiotracers
  • Small-animal SPECT
  • γ-ray imaging detector

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine

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