Abstract
In this chapter, we provide an overview of small-animal single-photon emission computed tomography (SPECT) applications and instrumentation. To reflect the recent expansion of both research and commercial activity in SPECT, SPECT/CT, and SPECT/MRI devices for small animals, the chapter has been organized to provide some history and a basic overview of applications and commercial instruments followed by a description of basic hardware and image formation methods in SPECT. Design trends in small-animal SPECT devices are then discussed, and the chapter concludes with a brief discussion of future directions in the field.
Original language | English (US) |
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Title of host publication | Molecular Imaging |
Subtitle of host publication | Principles and Practice |
Publisher | Elsevier |
Pages | 65-87 |
Number of pages | 23 |
ISBN (Electronic) | 9780128163863 |
ISBN (Print) | 9780128163870 |
DOIs | |
State | Published - Jan 1 2021 |
Keywords
- Collimation aperture
- Maximum likelihood reconstruction
- Multimodality imaging
- Radiotracers
- Small-animal SPECT
- γ-ray imaging detector
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology
- General Medicine