@inbook{7ba8f1366c4d40bfb9a51c490e3d01b0,
title = "Slipper snail tales: How Crepidula fornicata and Crepidula atrasolea became model molluscs",
abstract = "Despite the great abundance and diversity of molluscs, only a few have attained “model research organism” status. One of those species is the slipper snail Crepidula fornicata. Its embryos were first used for classical lineage tracing studies in the late 19th century, and over a 100 years later they were “re-discovered” by our labs and used for modern fate mapping, gene perturbation, in vivo imaging, transcriptomics, and the first application of CRISPR/Cas9-mediated genome editing among the Spiralia/Lophotrochozoa. Simultaneously, other labs made extensive examinations of taxonomy, phylogeny, ecology, life-history, mode of development, larval feeding behavior, and responses to the environment in members of the family Calyptraeidae, which includes the genus Crepidula. Recently, we developed tools, resources, and husbandry protocols for another, direct-developing species, Crepidula atrasolea. This species is an ideal “lab rat” among molluscs. Together these species will be valuable for probing the cellular and molecular mechanisms underlying molluscan biology and evolution.",
keywords = "Aquaculture, Crepidula, Eco-evo-devo, Evo-devo, Gene regulatory network, Lophotrochozoa, Marine Biological Laboratory, Mollusc, Morphogenesis, Spiral cleavage, Spiralia",
author = "Lyons, {Deirdre C.} and Henry, {Jonathan Q.}",
note = "Funding Information: We thank current lab members—especially Grant Batzel, Stephanie Neal, Hereroa Johnston, Maryna Lesoway, and Rebecca Lopez-Anido—for contributing ideas, images, and editing for this manuscript. We especially thank Kim Perry for her many years of work and collaboration on much of the research reviewed here. We thank Elaine Seaver for reminding J.Q. Henry and M.Q. Martindale that C. fornicata was readily available in the Marine Resource Center at the MBL. We acknowledge many Directors of the Marine Biological Laboratory's Embryology course (Drs. Joel Rothman, Richard Harland, Lee Niswander, Nipam Patel, Richard Behringer, Alejandro Sanchez-Alverado, Richard Schneider, David Sherwood, and Carole LaBonne) who deserve perennial thanks for their continued support in hosting us over so many summers. D.C. Lyons is indebted to Leslie Babonis and Seabird McKeon for helping to collect C. atrasolea, and to Dr. David R. McClay for his support. This work was supported by National Science Foundation grants IOS-1558061 and IOS-1827533 to J.Q. Henry (J.J. Henry). This work was also supported by National Science Foundation CAREER grant IOS-1943606 and National Institute of Health MIRA grant R35-GM133673 to D.C. Lyons. Lastly, we acknowledge the inspiration provided by Dr. Sebastian Beroe. Funding Information: We thank current lab members?especially Grant Batzel, Stephanie Neal, Hereroa Johnston, Maryna Lesoway, and Rebecca Lopez-Anido?for contributing ideas, images, and editing for this manuscript. We especially thank Kim Perry for her many years of work and collaboration on much of the research reviewed here. We thank Elaine Seaver for reminding J.Q. Henry and M.Q. Martindale that C. fornicata was readily available in the Marine Resource Center at the MBL. We acknowledge many Directors of the Marine Biological Laboratory's Embryology course (Drs. Joel Rothman, Richard Harland, Lee Niswander, Nipam Patel, Richard Behringer, Alejandro Sanchez-Alverado, Richard Schneider, David Sherwood, and Carole LaBonne) who deserve perennial thanks for their continued support in hosting us over so many summers. D.C. Lyons is indebted to Leslie Babonis and Seabird McKeon for helping to collect C. atrasolea, and to Dr. David R. McClay for his support. This work was supported by National Science Foundation grants IOS-1558061 and IOS-1827533 to J.Q. Henry (J.J. Henry). This work was also supported by National Science Foundation CAREER grant IOS-1943606 and National Institute of Health MIRA grant R35-GM133673 to D.C. Lyons. Lastly, we acknowledge the inspiration provided by Dr. Sebastian Beroe. Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",
year = "2022",
month = jan,
doi = "10.1016/bs.ctdb.2021.12.013",
language = "English (US)",
isbn = "9780128201541",
series = "Current Topics in Developmental Biology",
publisher = "Academic Press Inc.",
pages = "375--399",
editor = "Bob Goldstein and Mansi Srivastava",
booktitle = "Emerging Model Systems in Developmental Biology",
address = "United States",
}