Size-sensitive sorting of microparticles through control of flow geometry

Cheng Wang, Shreyas V. Jalikop, Sascha Hilgenfeldt

Research output: Contribution to journalArticle

Abstract

We demonstrate a general concept of flow manipulation in microfluidic environments, based on controlling the shape and position of flow domains in order to force switching and sorting of microparticles without moving parts or changes in design geometry. Using microbubble acoustic streaming, we show that regulation of the relative strength of streaming and a superimposed Poiseuille flow allows for size-selective trapping and releasing of particles, with particle size sensitivity much greater than what is imposed by the length scales of microfabrication. A simple criterion allows for quantitative tuning of microfluidic devices for switching and sorting of particles of desired size.

Original languageEnglish (US)
Article number034101
JournalApplied Physics Letters
Volume99
Issue number3
DOIs
StatePublished - Jul 18 2011

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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