Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener

Jung Heon Lee, Daryl P. Wernette, Mehmet V. Yigit, Juewen Liu, Zidong Wang, Yi Lu

Research output: Contribution to journalArticlepeer-review

Abstract

(Figure Presented) Going for double gold: Precise control of the positions of and distances between gold nanoparticles (AuNP; gold spheres in picture) is achieved by linking the AuNPs to phosphorothioate-modified DNA (green and red helices) with a bifunctional fastener. The distance between AuNPs is controlled simply by changing the position of the modifications on the DNA template.

Original languageEnglish (US)
Pages (from-to)9006-9010
Number of pages5
JournalAngewandte Chemie - International Edition
Volume46
Issue number47
DOIs
StatePublished - Dec 14 2007

Keywords

  • DNA
  • Nanostructures
  • Nanotechnology
  • Self-assembly
  • Surface chemistry

ASJC Scopus subject areas

  • Chemistry(all)

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