Single-molecule imaging with quantum dots

Mohammad U. Zahid, Andrew M Smith

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Quantum dots (QDs) are a class of fluorescent nanocrystal with unique optical and electronic properties (Smith et al. 2008; Smith and Nie 2009a). Originally investigated as components for light-emitting devices, solar cells, and catalysts in the early 1980s, these particles were introduced in 1998 as optical tags for bioimaging and biological detection (Chan and Nie 1998; Bruchez et al. 1998). Over the ensuing 15 years, their most significant contribution to biomedicine has been in the field of single-molecule fluorescence microscopy, for which they have filled a major need for bright fluorescent probes with long-term photostability. These particles are now widely used for imaging the dynamics of individual molecules and the interactions between molecules in complex biological environments.

Original languageEnglish (US)
Title of host publicationOptical Nanoscopy and Novel Microscopy Techniques
PublisherCRC Press
Pages135-160
Number of pages26
ISBN (Electronic)9781466586307
ISBN (Print)9781466586291
DOIs
StatePublished - Jan 1 2014

Fingerprint

Quantum Dots
biomedicine
Fluorescent Dyes
Fluorescence Microscopy
Nanoparticles
Semiconductor quantum dots
quantum dots
electronics
Imaging techniques
Light
Equipment and Supplies
Molecules
interaction
molecules
Fluorescence microscopy
Electronic properties
Nanocrystals
Solar cells
nanocrystals
Optical properties

ASJC Scopus subject areas

  • Social Sciences(all)
  • Physics and Astronomy(all)
  • Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Zahid, M. U., & Smith, A. M. (2014). Single-molecule imaging with quantum dots. In Optical Nanoscopy and Novel Microscopy Techniques (pp. 135-160). CRC Press. https://doi.org/10.1201/b17421

Single-molecule imaging with quantum dots. / Zahid, Mohammad U.; Smith, Andrew M.

Optical Nanoscopy and Novel Microscopy Techniques. CRC Press, 2014. p. 135-160.

Research output: Chapter in Book/Report/Conference proceedingChapter

Zahid, MU & Smith, AM 2014, Single-molecule imaging with quantum dots. in Optical Nanoscopy and Novel Microscopy Techniques. CRC Press, pp. 135-160. https://doi.org/10.1201/b17421
Zahid MU, Smith AM. Single-molecule imaging with quantum dots. In Optical Nanoscopy and Novel Microscopy Techniques. CRC Press. 2014. p. 135-160 https://doi.org/10.1201/b17421
Zahid, Mohammad U. ; Smith, Andrew M. / Single-molecule imaging with quantum dots. Optical Nanoscopy and Novel Microscopy Techniques. CRC Press, 2014. pp. 135-160
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