Single molecule fluorescence study of DNA helicase activity

T. Ha, H. P. Babcock, W. Cheng, T. M. Lohman, S. Chu

Research output: Contribution to conferencePaperpeer-review


The molecular mechanism of helicases at the single molecule level was studied using fluorescence resonance energy transfer (FRET) between two dyes, donor and acceptor. Measured FRET efficiency was shown to be an indicator of the distance between two dyes, revealing the extent and the time-course of unwinding.

Original languageEnglish (US)
Number of pages2
StatePublished - 2000
EventConference on Lasers and Electro-Optics (CLEO 2000) - San Francisco, CA, USA
Duration: May 7 2000May 12 2000


OtherConference on Lasers and Electro-Optics (CLEO 2000)
CitySan Francisco, CA, USA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Condensed Matter Physics
  • Electrical and Electronic Engineering


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