Simultaneous reconstruction of speed-of-sound and optical absorption properties in photoacoustic tomography via a time-domain iterative algorithm

Jin Zhang, Kun Wang, Yongyi Yang, Mark A. Anastasio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Photoacoustic tomography (PAT) is a hybrid imaging modality that combines the advantages of both optical imaging and ultrasound imaging techniques. Most existing reconstruction algorithms assume the speed-of-sound distribution within the object is homogeneous. In certain practical applications, this assumption may not be valid and will result in conspicuous image artifacts. In this work, we investigate the possibility of simultaneously estimating the speed-of-sound and optical absorption properties from data acquired in a PAT experiment. We propose and numerically implement a time-domain iterative algorithm that can reconstruct both the speedof-sound and optical absorption distribution, by use of a priori information regarding the geometry of the speed-of-sound map. Computer-simulation results are presented to demonstrate the efficacy of the proposed reconstruction method.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
DOIs
StatePublished - Apr 23 2008
Externally publishedYes
Event9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 - San Jose, CA, United States
Duration: Jan 20 2008Jan 23 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6856
ISSN (Print)1605-7422

Conference

Conference9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008
Country/TerritoryUnited States
CitySan Jose, CA
Period1/20/081/23/08

Keywords

  • Image reconstruction
  • Phase-aberration correction
  • Photoacoustic tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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