Simultaneous prognosis and exploratory analysis of multiple chronic conditions using clinical notes

Shalmali Joshi, Oluwasanmi Koyejo, Kristine Resurreccion, Joydeep Ghosh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose a novel approach for simultaneous exploratory analysis and prognosis of multiple chronic conditions that can enable healthcare professionals to harness the vast amounts of medical data available in electronic health records (EHRs) in a comprehensive manner for early treatment, the discovery of previously unknown symptoms and exploration of new associations in the context of individual chronic conditions. In particular, this manuscript focuses on the use of early clinical notes available in EHRs to diagnose multiple chronic conditions. While most methods for EHR analysis have focused on single disease predictions, multiple conditions called co morbidities tend to occur simultaneously with the primary chronic condition in many patients. To this end, we model each chronic condition as a latent variable in a novel supervised topic model which results in the prediction of multiple illnesses associated with each patient. In addition, the supervised topic model also provides an interpretable graphical visualization of each chronic condition for detailed exploratory analysis. We compare the proposed model to relevant state-of-the art methods, demonstrating both its quantitative and qualitative merits.

Original languageEnglish (US)
Title of host publicationProceedings - 2015 IEEE International Conference on Healthcare Informatics, ICHI 2015
EditorsWai-Tat Fu, Prabhakaran Balakrishnan, Sanda Harabagiu, Fei Wang, Jaideep Srivatsava
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages243-252
Number of pages10
ISBN (Electronic)9781467395489
DOIs
StatePublished - Dec 8 2015
Externally publishedYes
Event3rd IEEE International Conference on Healthcare Informatics, ICHI 2015 - Dallas, United States
Duration: Oct 21 2015Oct 23 2015

Publication series

NameProceedings - 2015 IEEE International Conference on Healthcare Informatics, ICHI 2015

Other

Other3rd IEEE International Conference on Healthcare Informatics, ICHI 2015
Country/TerritoryUnited States
CityDallas
Period10/21/1510/23/15

ASJC Scopus subject areas

  • Health Informatics

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