This Minireview provides an overview on the development of silyl ketene imines and their recent applications in catalytic, enantioselective reactions. The unique structure of the ketene imine allows a diverse range of reactivity patterns and provides solutions to existing challenges in the enantioselective construction of quaternary stereogenic carbon centers and cross-benzoin adducts. A variety of reactions for which silyl ketene imines have been applied are presented with an overall goal of inspiring new uses for these underutilized nucleophiles.
|Original language||English (US)|
|Number of pages||13|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Oct 1 2012|
- asymmetric catalysis
- synthetic methods
ASJC Scopus subject areas