Silicon field effect transistors as dual-use sensor-heater hybrids

Bobby Reddy, Oguz H. Elibol, Pradeep R. Nair, Brian R. Dorvel, Felice Butler, Zahab Ahsan, Donald E. Bergstrom, Muhammad A. Alam, Rashid Bashir

Research output: Contribution to journalArticle

Abstract

We demonstrate the temperature mediated applications of a previously proposed novel localized dielectric heating method on the surface of dual purpose silicon field effect transistor (FET) sensor-heaters and perform modeling and characterization of the underlying mechanisms. The FETs are first shown to operate as electrical sensors via sensitivity to changes in pH in ionic fluids. The same devices are then demonstrated as highly localized heaters via investigation of experimental heating profiles and comparison to simulation results. These results offer further insight into the heating mechanism and help determine the spatial resolution of the technique. Two important biosensor platform applications spanning different temperature ranges are then demonstrated: a localized heat-mediated DNA exchange reaction and a method for dense selective functionalization of probe molecules via the heat catalyzed complete desorption and reattachment of chemical functionalization to the transistor surfaces. Our results show that the use of silicon transistors can be extended beyond electrical switching and field-effect sensing to performing localized temperature controlled chemical reactions on the transistor itself.

Original languageEnglish (US)
Pages (from-to)888-895
Number of pages8
JournalAnalytical chemistry
Volume83
Issue number3
DOIs
StatePublished - Feb 1 2011

Fingerprint

Silicon
Field effect transistors
Transistors
Sensors
Dielectric heating
Heating
Biosensors
Temperature
Chemical reactions
Desorption
Molecules
Fluids
DNA
Hot Temperature

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Reddy, B., Elibol, O. H., Nair, P. R., Dorvel, B. R., Butler, F., Ahsan, Z., ... Bashir, R. (2011). Silicon field effect transistors as dual-use sensor-heater hybrids. Analytical chemistry, 83(3), 888-895. https://doi.org/10.1021/ac102566f

Silicon field effect transistors as dual-use sensor-heater hybrids. / Reddy, Bobby; Elibol, Oguz H.; Nair, Pradeep R.; Dorvel, Brian R.; Butler, Felice; Ahsan, Zahab; Bergstrom, Donald E.; Alam, Muhammad A.; Bashir, Rashid.

In: Analytical chemistry, Vol. 83, No. 3, 01.02.2011, p. 888-895.

Research output: Contribution to journalArticle

Reddy, B, Elibol, OH, Nair, PR, Dorvel, BR, Butler, F, Ahsan, Z, Bergstrom, DE, Alam, MA & Bashir, R 2011, 'Silicon field effect transistors as dual-use sensor-heater hybrids', Analytical chemistry, vol. 83, no. 3, pp. 888-895. https://doi.org/10.1021/ac102566f
Reddy B, Elibol OH, Nair PR, Dorvel BR, Butler F, Ahsan Z et al. Silicon field effect transistors as dual-use sensor-heater hybrids. Analytical chemistry. 2011 Feb 1;83(3):888-895. https://doi.org/10.1021/ac102566f
Reddy, Bobby ; Elibol, Oguz H. ; Nair, Pradeep R. ; Dorvel, Brian R. ; Butler, Felice ; Ahsan, Zahab ; Bergstrom, Donald E. ; Alam, Muhammad A. ; Bashir, Rashid. / Silicon field effect transistors as dual-use sensor-heater hybrids. In: Analytical chemistry. 2011 ; Vol. 83, No. 3. pp. 888-895.
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