The silicon-directed Nazarov cyclization of the optically active β′-silyldivinyl ketones (+)-1 and (-)-1 proceeded with near perfect stereoselectivity. The direction of conrotatory electrocyclic ring closure was controlled by the remote silyl group such that carbon-carbon bond formation occurred in an anti SE′ sense to the silicon electrofuge.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Organic Chemistry|
|State||Published - Dec 1 1990|
ASJC Scopus subject areas
- Organic Chemistry