Abstract
The design, synthesis, and characterization of a novel polymeric nanostructured material bearing surface-attached integrin antagonists are demonstrated. The covalent coupling of a complex and biologically active small molecule to a well-defined nanostructured material combines the elegance of synthetic organic chemistry with the state-of-the-art polymer chemistry. This unique material offers potential in targeting to tumor neovasculature and delivery of diagnostic and therapeutic agents.
Original language | English (US) |
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Pages (from-to) | 7109-7115 |
Number of pages | 7 |
Journal | Macromolecules |
Volume | 37 |
Issue number | 19 |
DOIs | |
State | Published - Sep 21 2004 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry
- Polymers and Plastics
- Inorganic Chemistry
- Materials Chemistry