TY - JOUR
T1 - Severe Laryngotracheobronchitis Complicating Measles
AU - Fortenberry, James D.
AU - Mariscalco, M. Michele
AU - Louis, Penelope T.
AU - Stein, Fernando
AU - Jones, John K.
AU - Jefferson, Larry S.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1992/9
Y1 - 1992/9
N2 - To determine the incidence of severe measles-related laryngotracheobronchitis in patients hospitalized during a recent measles epidemic and to evaluate factors associated with severity of airway injury and its management. —Clinical description of patient series. Setting.—Children's hospital and county general hospital, Houston, Tex. —One hundred twenty-four children (aged 1 month to 19 years) admitted with a diagnosis of measles. —None. —Twenty-seven patients had significant laryngotracheobronchitis, including 10 who had not received appropriate immunization. Six patients required endotracheal intubation for relief of upper airway obstruction. The median age of patients requiring intubation was 12 months (range, 4 to 24 months). Two patients died of complications of superinfection. Two patients survived but required prolonged intubation. Two patients underwent early diagnostic laryngoscopy and bronchoscopy and required shorter artificial airway maintenance. —Severe laryngotracheobronchitis frequently occurs in patients younger than 2 years hospitalized with measles and may be related to bacterial or viral superinfection. Early diagnostic laryngoscopy and bronchoscopy for injury assessment and possible endotracheal tube exchange are recommended and, in some severe cases, tracheostomy should be considered to shorten artificial airway maintenance and decrease the incidence of airway complications.
AB - To determine the incidence of severe measles-related laryngotracheobronchitis in patients hospitalized during a recent measles epidemic and to evaluate factors associated with severity of airway injury and its management. —Clinical description of patient series. Setting.—Children's hospital and county general hospital, Houston, Tex. —One hundred twenty-four children (aged 1 month to 19 years) admitted with a diagnosis of measles. —None. —Twenty-seven patients had significant laryngotracheobronchitis, including 10 who had not received appropriate immunization. Six patients required endotracheal intubation for relief of upper airway obstruction. The median age of patients requiring intubation was 12 months (range, 4 to 24 months). Two patients died of complications of superinfection. Two patients survived but required prolonged intubation. Two patients underwent early diagnostic laryngoscopy and bronchoscopy and required shorter artificial airway maintenance. —Severe laryngotracheobronchitis frequently occurs in patients younger than 2 years hospitalized with measles and may be related to bacterial or viral superinfection. Early diagnostic laryngoscopy and bronchoscopy for injury assessment and possible endotracheal tube exchange are recommended and, in some severe cases, tracheostomy should be considered to shorten artificial airway maintenance and decrease the incidence of airway complications.
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U2 - 10.1001/archpedi.1992.02160210042018
DO - 10.1001/archpedi.1992.02160210042018
M3 - Article
C2 - 1514548
AN - SCOPUS:0026640276
SN - 0096-8994
VL - 146
SP - 1040
EP - 1043
JO - American Journal of Diseases of Children
JF - American Journal of Diseases of Children
IS - 9
ER -