Serum protein concentrations and enzyme activities, as functions of age and sex, in Sinclair(S 1) miniature swine

M. E. Tumbleson, D. P. Hutcheson, C. C. Middleton

Research output: Contribution to journalArticle

Abstract

Venous blood samples were collected from 60 male and 60 female Sinclair(S 1) miniature swine from 1 through 36 months of age. Serum total protein concentration increased linearly from 1 through 10 months of age and remained stable thereafter with no sex related difference. Serum albumin concentration decreased from 1 through 3 months, increased from 3 through 8 months and decreased from 14 through 36 months. From 2 through 36 months, serum alpha globulin concentration decreased; whereas, serum beta globulin concentration increased. Serum gamma globulin concentration increased markedly from 1 through 3 months and continued to increase through 36 months of age. From 10 through 36 months, males had a greater mean serum gamma globulin concentration than did females. Serum total globulin concentration increased most rapidly from 1 through 3 months, less rapidly from 3 through 18 months and remained stable thereafter. Serum albumin/globulin ratio decreased sharply from 1 through 3 months and continued to decrease from 6 through 36 months with females having a greater mean concentration than males. Serum glutamic oxaloacetic transaminase activity decreased from 1 through 30 months with males having a greater mean activity than females from 7 through 36 months of age. Serum alkaline phosphatase activity decreased from 1 through 36 months of age with no sex related difference. Serum lactic dehydrogenase activity decreased from 1 through 30 months with females having a greater mean activity than males from 24 through 36 months of age.

Original languageEnglish (US)
Pages (from-to)53-68
Number of pages16
JournalGrowth
Volume40
Issue number1
StatePublished - Dec 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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